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Mechanism: Selective β1-blockade → reduces heart rate, cardiac output, BP, and contractility by inhibiting catecholamine effects.
Less interference with insulin release & carbohydrate metabolism than non-selective β-blockers.
Hypertension: 100–400 mg/day (single or divided doses)
Angina: 50–100 mg, 2–3× daily
Arrhythmias: 50 mg, 2–3× daily (up to 300 mg/day)
Hyperthyroidism: 50 mg, 4× daily (reduce when euthyroid)
MI: IV 5 mg q2min ×3 doses → oral 50 mg q6h for 48 h → maintenance 200 mg/day
Extended-release: 25–100 mg once daily
Heart Failure: Start 12.5–25 mg daily; titrate weekly
Common: fatigue, dizziness, depression, diarrhea, rash, bradycardia
Others: insomnia, nausea, constipation, blurred vision, decreased libido, AV block
Category C: Use only if clearly needed
Excreted in small amounts in breast milk → use with caution
Cool, dry place, protected from light
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.